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主营:研究并生产荧光和发光探针,信号转导研究的试剂
℡ 4000-520-616
℡ 4000-520-616
AAT Bioquest/Leu-AMC [L-Leucine-7-amido-4-methylcoumarin] *CAS 62480-44-8*/13445/10 mg
产品编号:13445
市  场 价:¥42060.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
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美  元  价:$2103.00
品      牌: AAT Bioquest
公      司:AAT Bioquest
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AAT Bioquest/Leu-AMC [L-Leucine-7-amido-4-methylcoumarin] *CAS 62480-44-8*/13445/10 mg
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Overview
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Ex/Em(nm)351/430
MW324.80
CAS#62480-44-8
SolventDMSO
StorageF/D/L
CategoryEnzymeDetection
PeptidasesandProteases
Related
Leu-AMCisafluorogenicsubstrateforleucineaminopeptidase.Uponthehydrolysisbyproteases,Leu-AMCreleasesthestronglyfluorescentAMCfluorophorethatcanbereADIlydetectedwithEx/Em=350/430nm.
SpectrumAdvancedSpectrumViewer

Sorry,yourbrowserdoesnotsupportinlineSVG.RelativeIntensity(%)100806040200Sorry,yourbrowserdoesnotsupportinlineSVG.
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Wavelength(nm)

References&Citations
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  1. WangKD,WangKH,ZhouND,TianYP.(2016)SecretoryExpression,Purification,Characterization,andApplicationofanAspergillusoryzaeProlylAminopeptidaseinBacillussubtilis.ApplBiochemBiotechnol.
  2. MunkhjargalT,IshizakiT,GuSwantoA,TakemaeH,YokoyamaN,IgarashiI.(2016)MolecularandbiochemicalcharacterizationofmethionineaminopeptidaseofBabesiabovisasapotentdrugtarget.VetParasitol,221,14.
  3. WangX,ShiL,DengY,QuM,MaoS,XuL,XuW,FangC.(2015)Inhibitionofleucineaminopeptidase3suppressesinvasionofovariancancercellsthroughdown-regulationoffascinandMMP-2/9.EurJPharmacol,768,116.
  4. LeeYR,NaBK,MoonEK,SongSM,JooSY,KongHH,GooYK,ChungDI,HongY.(2015)EssentialRoleforanM17LeucineAminopeptidaseinEncystationofAcanthamoebacastellanii.PLoSOne,10,e0129884.
  5. AbogeGO,CaoS,TerkawiMA,MasataniT,GooY,AbouLailaM,NishikawaY,IgarashiI,SuzukiH,XuanX.(2015)MolecularCharacterizationofBabesiabovisM17LeucineAminopeptidaseandInhibitionofBabesiaGrowthbyBestatin.JParasitol,101,536.
  6. SahiS,RajU,ChaudharyM,NainV.(2014)ModellingofhumanleucylaminopeptidasesforinsilicoofftargetbindinganalysisofpotentialPlasmodiumfalciparumleucineaminopeptidase(PfA-M17)specificinhibitors.RecentPatEndocrMetabImmuneDrugDiscov,8,191.
  7. LiewSM,TayST,PuthuchearySD.(2013)EnzymaticandmolecularcharacterisationofleucineaminopeptidaseofBurkholderiapseudomallei.BMCMicrobiol,13,110.
  8. MaC,JinK,CaoJ,ZhangL,LiX,XuW.(2013)NovelleucineureidoderivativesasinhibitorsofaminopeptidaseN(APN).BioorgMedChem,21,1621.
  9. HalderAK,SahaA,JhaT.(2013)ExplorationofstructuralandphysicochemicalrequirementsandsearchofvirtualhitsforaminopeptidaseNinhibitors.MolDivers,17,123.
  10. CarrollRK,VeillardF,GagneDT,LindenmuthJM,PorebaM,DragM,PotempaJ,ShawLN.(2013)TheStaphylococcusaureusleucineaminopeptidaseislocalizedtothebacterialcytosolanddemonstratesabroadsubstraterangethatextendsbeyondleucine.BiolChem,394,791.

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