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主营:研究并生产荧光和发光探针,信号转导研究的试剂
℡ 4000-520-616
℡ 4000-520-616
AAT Bioquest/MCLA [2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one, hydrochloride] *CAS 128322-44-1*/152
产品编号:15250
市  场 价:¥27560.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$1378.00
品      牌: AAT Bioquest
公      司:AAT Bioquest
公司分类:
AAT Bioquest/MCLA [2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one, hydrochloride] *CAS 128322-44-1*/152
商品介绍
Overview
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Ex/Em(nm)430/546
MW291.73
CAS#128322-44-1
SolventDMSO
StorageF/D/L
CategoryEnzymeDetection
RedoxEnzymes
RelatedCellSignalingMolecules
ReactiveOxygenSpecies
BiochemicalAssays
MCLAhasbeenusedtoassesssuperoxideformationinavarietyofconditions,includingneutrophilandmacrophageactivation,culturedcellsandvasculartissue.ByusingMCLAchemiluminescence,invivosuperoxideproductionhasbeenreportedfromthesurfaceofliver,intestine,heartandlung.MCLA-amplifiedchemiluminescenceisalsousedtodeterminetheextracellularsuperoxideproductionfromspermatozoa.
References&Citations
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1.   TeranishiK.(2006)Developmentofimidazopyrazinonered-chemiluminescentprobesfordetectingsuperoxideanionsviaachemiluminescenceresonanceenergytransfermethod.Luminescence.

2.   MasuiS,MajimaT,NakamuraK,Ito-KuwaS,TakeoK,AokiS.(2004)ChemiluminescentvisualizationofsuperoxidegeneratedbyCandidaalbicans.MedMycol,42,427.

3.   OkaiY,SatoEF,Higashi-OkaiK,InoueM.(2004)Effectofendocrinedisruptorpara-nonylphenolonthecellgrowthandoxygenrADIcalgenerationinEscherichiacolimutantcellsdeficientincatalaseandsuperoxidedismutase.FreeRadicBiolMed,37,1412.

4.   YamaguchiK,UematsuD,ItohY,WatanabeS,FukuuchiY.(2002)Invivomeasurementofsuperoxideinthecerebralcortexduringanoxia-reoxygenationandischemia-reperfusion.KeioJMed,51,201.

5.   HasegawaT,KikuyamaM,SakuraiK,KambayashiY,AdachiM,SaniabadiAR,KuwanoH,NakanoM.(2002)MechanismofsuperoxideanionproductionbyhepaticsinusoidalendothelialcellsandKupffercellsduringshort-termethanolperfusionintherat.Liver,22,321.

6.   SakuraiT,TerakawaS.(2002)SuperoxideproductionintheisletofLangerhansdetectedbytheMCLAchemiluminescencemethod.MethodsMolBiol,196,203.

7.   YoshidaT,TanakaM,OkamotoK.(2002)ImmunoglobulinGinducesmicroglialsuperoxideproduction.NeurolRes,24,361.

8.   HasegawaT,NakanoM,HashimotoT,HiraishiK,SuzukiK,KuwanoH.(2001)SinusoidalendothelialcellinjurybysuperoxideanionandironinthePropionibacteriumacnes-pretreatedandlipopolysaccharide-stimulatedratliver.Liver,21,415.

9.   AokiS,Ito-KuwaS,NakamuraK,NakamuraY,VidottoV,TakeoK.(2002)ChemiluminescenceofsuperoxidegeneratedbyCandidaalbicans:differentialeffectsofthesuperoxidegeneratorparaquatonawild-typestrainandarespiratorymutant.MedMycol,40,13.

10.   MasudaH,TanakaT,TateishiM,NaitoM,TamaiH.(2001)Detectionandcytotoxicityofcisplatin-inducedsuperoxideanioninmonolayerculturesofahumanovariancancercellline.CancerChemotherPharmacol,47,155.


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