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主营:研究并生产荧光和发光探针,信号转导研究的试剂
℡ 4000-520-616
℡ 4000-520-616
AAT Bioquest/(-)-Blebbistatin *CAS#: 856925-71-8*/80001/1 mg
产品编号:80001
市  场 价:¥27560.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$1378.00
品      牌: AAT Bioquest
公      司:AAT Bioquest
公司分类:
AAT Bioquest/(-)-Blebbistatin *CAS#: 856925-71-8*/80001/1 mg
商品介绍
Overview
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Ex/Em(nm)None/None
MW292.33
CAS#856925-71-8
SolventN/A
StorageF/D/L
CategoryEnzymeDetection
ProteinKinases
RelatedBiochemicalAssays
(-)-Blebbistatinisacell-permeableinhibitorfornonmusclemyosinIIATPasewithIC50of2µM.Itdoesnotinhibitmyosinlightchainkinase,inhibitscontractionofthecleavagefurrowwithoutdisruptingmitosisorcontractileringassembly.
References&Citations
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1.   LvY,LuS,LuT,KouJ,YuB.(2013)HomologymodelofnonmusclemyosinheavychainIIAandbindingmodeanalysiswithitsinhibitorblebbistatin.JMolModel,19,1801.

2.   BrackKE,NarangR,WinterJ,NgGA.(2013)Themechanicaluncouplerblebbistatinisassociatedwithsignificantelectrophysiologicaleffectsintheisolatedrabbitheart.ExpPhysiol,98,1009.

3.   SwiftLM,AsfourH,PosnackNG,ArutunyanA,KayMW,SarvazyanN.(2012)Propertiesofblebbistatinforcardiacopticalmappingandotherimagingapplications.PflugersArch,464,503.

4.   MikulichA,KavaliauskieneS,JuzenasP.(2012)Blebbistatin,amyosininhibitor,isphototoxictohumancancercellsunderexposuretobluelight.BiochimBiophysActa,1820,870.

5.   BrinesL,Such-MiquelL,GallegoD,TraperoI,DelCantoI,ZarzosoM,SolerC,PelechanoF,CanovesJ,AlberolaA,SuchL,ChorroFJ.(2012)Modificationsofmechanoelectricfeedbackinducedby2,3-butanedionemonoximeandBlebbistatininLangendorff-perfusedrabbithearts.ActaPhysiol(Oxf),206,29.

6.   MatsuiY,NakayamaY,OkamotoM,FukumotoY,YamaguchiN.(2012)Enrichmentofcellpopulationsinmetaphase,anaphase,andtelophasebysynchronizationusingnocodazoleandblebbistatin:anovelmethodsuitableforexaminingdynamicchangesinproteinsduringmitoticprogression.EurJCellBiol,91,413.

7.   LouQ,LiW,EfimovIR.(2012)TheroleofdynamicinstABIlityandwavelengthinarrhythmiamaintenanceasrevealedbypanoramicimagingwithblebbistatinvs.2,3-butanedionemonoxime.AmJPhysiolHeartCircPhysiol,302,H262.

8.   LangE,QadriSM,ZelenakC,GuS,RotteA,DraegerA,LangF.(2011)Inhibitionofsuicidalerythrocytedeathbyblebbistatin.AmJPhysiolCellPhysiol,301,C490.

9.   LawsonCP,SlawinAM,WestwoodNJ.(2011)ApplicationofthecoppercatalysedN-arylationofamidinesinthesynthesisofanaloguesofthechemicaltool,blebbistatin.ChemCommun(Camb),47,1057.

10.   HuangJ,ZhangJ,PathakA,LiJ,StoufferGA.(2011)Perivasculardeliveryofblebbistatinreducesneointimalhyperplasiaaftercarotidinjuryinthemouse.JPharmacolExpTher,336,116.


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AAT Bioquest常用产品报价单

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