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主营:研究并生产荧光和发光探针,信号转导研究的试剂
℡ 4000-520-616
℡ 4000-520-616
AAT Bioquest/Resorufin Phosphocholine/11640/1 mg
产品编号:11640
市  场 价:¥85560.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$4278.00
品      牌: AAT Bioquest
公      司:AAT Bioquest
公司分类:
AAT Bioquest/Resorufin Phosphocholine/11640/1 mg
商品介绍
Overview
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Ex/Em(nm)575/590
MW378.32
CAS#N/A
SolventWater
StorageF/D/L
CategoryEnzymeDetection
Phosphodiesterases
RelatedBiochemicalAssays
GlycerophosphocholinephosphodiesterasereleasephosphocholinefromresorufinphosphocholinetogivethehighlyfluorescentresorufinthatcanbereADIlymonitoredbyeitherfluorescenceorabsorption.Thisfluorogenicphosphodiesterasesubstratecanbeconvenientlyusedforscreeningtheinhibitorsofglycerophosphocholinephosphodiesterase.ItcanalsobeusedformonitoringtheactivitiesofphospholipaseDincombinationwithaphosphatase.PhospholipaseDhydrolyzesresorufinphosphocholinetoresorufinphosphate,whichinthepresenceofanacidphosphatasegeneratesresorufin.Thus,resorufinphosphocholinecanalsobeusedformonitoringphospholipaseDinsourcesthatdonotalsocontainhighlevelsofphospholipaseC.
SpectrumAdvancedSpectrumViewer

Sorry,yourbrowserdoesnotsupportinlineSVG.RelativeIntensity(%)100806040200Sorry,yourbrowserdoesnotsupportinlineSVG.
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References&Citations
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1.   MarchandC,LeaWA,JadhavA,DexheimerTS,AustinCP,IngleseJ,PommierY,SimeonovA.(2009)Identificationofphosphotyrosinemimeticinhibitorsofhumantyrosyl-DNAphosphodiesteraseIbyanovelAlphaScreenhigh-throughputassay.MolCancerTher,8,240.

2.   DallasC,GerbiA,TencaG,JuchauxF,BernardFX.(2008)Lipolyticeffectofapolyphenoliccitrusdryextractofredorange,grapefruit,orange(SINETROL)inhumanbodyfatadipocytes.MechanismofactionbyinhibitionofcAMP-phosphodiesterase(PDE).Phytomedicine,15,783.

3.   Dell"AgliM,MaschiO,GalliGV,FagnaniR,DalCeroE,CarusoD,BosisioE.(2008)InhibitionofplateletaggregationbyoliveoilphenolsviacAMP-phosphodiesterase.BrJNutr,99,945.

4.   KaihoY,NishiguchiJ,KwonDD,ChancellorMB,AraiY,SnyderPB,YoshimuraN.(2008)Theeffectsofatype4phosphodiesteraseinhibitorandthemuscariniccholinergicantagoNISTtolterodinetartrateondetrusoroveractivityinfemaleratswithbladderoutletobstruction.BJUInt,101,615.

5.   TeramotoS,YamamotoH,YamaguchiY,IshiiM,HibiS,KumeH,OuchiY.(2008)Antiplateletcilostazol,aninhibitoroftypeIIIphosphodiesterase,improvesswallowingfunctioninpatientswithahistoryofstroke.JAmGeriatrSoc,56,1153.

6.   FujimuraM,LiuQ.(2007)Selectiveinhibitorsforphosphodiesterase3and4inantigen-inducedincreaseofcoughreflexsensitivityinguineapigs.PulmPharmacolTher,20,543.

7.   GhanemE,LiY,XuC,RaushelFM.(2007)CharacterizationofaphosphodiesterasecapableofhydrolyzingEA2192,themosttoxicdegradationproductofthenerveagentVX.Biochemistry,46,9032.

8.   KeppetipolaN,ShumanS.(2007)Characterizationofthe2",3"cyclicphosphodiesteraseactivitiesofClostridiumThermocellumpolynucleotidekinase-phosphataseandbacteriophagelamBDaphosphatase.NucleicAcidsRes,35,7721.

9.   RuckerB,AlmeidaME,LibermannTA,ZerbiniLF,WinkMR,SarkisJJ.(2007)Biochemicalcharacterizationofecto-nucleotidepyrophosphatase/phosphodiesterase(E-NPP,E.C.3.1.4.1)fromratheartleftventricle.MolCellBiochem,306,247.

10.   HoSM,TangWY,BelmontedeFraustoJ,PrinsGS.(2006)DevelopmentalexposuretoestradiolandbisphenolAincreasessusceptibilitytoprostatecarcinogenesisandepigeneticallyregulatesphosphodiesterasetype4variant4.CancerRes,66,5624.


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