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主营:研究并生产荧光和发光探针,信号转导研究的试剂
℡ 4000-520-616
℡ 4000-520-616
AAT Bioquest/CLF [Cholyl-Lys-Fluorescein]/36701/1 mg
产品编号:36701
市  场 价:¥85560.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$4278.00
品      牌: AAT Bioquest
公      司:AAT Bioquest
公司分类:
AAT Bioquest/CLF [Cholyl-Lys-Fluorescein]/36701/1 mg
商品介绍
Overview
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Ex/Em(nm)492/516
MW926.12
CAS#N/A
SolventDMSO
StorageF/D/L
CategoryTransporters
BileAcidTransporters
RelatedCellFunctionalAnalysis
BiochemicalAssays
CLFisafluorescein-labeledbileacidanalogthatcloselyparallelsthecellularbindinganduptakepropertiesofcholicacidderivatives.Itisadivalent"unipolar"anionicfluorescentmonohydroxybilesaltanalogwithphysical,BIOLOGicalandcholestaticpropertiesthataresimilartothoseoflithocholate,glycolithocholateandtheirderivativesandthusoffersapotentiallyusefulprobeforstudyingmechanismsofmonohydroxybilesalt-inducedcholestasisatthehepatocellularlevel.CLFiscurrentlyusedasatoolforthevisualizationofbileacidtransportwithinlivertissue.
SpectrumAdvancedSpectrumViewer

Sorry,yourbrowserdoesnotsupportinlineSVG.RelativeIntensity(%)100806040200Sorry,yourbrowserdoesnotsupportinlineSVG.
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References&Citations
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1.   MitaS,SuzukiH,AkitaH,HayashiH,OnukiR,HofmannAF,SugiyamaY.(2006)InhibitionofbileacidtransportacrossNa+/taurocholatecotransportingpolypeptide(SLC10A1)andbilesaltexportpump(ABCB11)-coexpressingLLC-PK1cellsbycholestasis-inducingdrugs.DrugMetabDispos,34,1575.

2.   PerezLM,MilkiewiczP,EliasE,ColemanR,SanchezPozziEJ,RomaMG.(2006)Oxidativestressinducesinternalizationofthebilesaltexportpump,Bsep,andbilesaltsecretoryfailureinisolatedrathepatocytecouplets:aroleforproteinkinaseCandpreventionbyproteinkinaseA.ToxicolSci,91,150.

3.   WangW,SorokaCJ,MennoneA,RahnerC,HarryK,PypaertM,BoyerJL.(2006)RADIxinisrequiredtomaintainapicalcanalicularmembranestructureandfunctioninrathepatocytes.Gastroenterology,131,878.

4.   SidlerPfandlerMA,HochliM,InderbitzinD,MeierPJ,StiegerB.(2004)Smallhepatocytesinculturedeveloppolarizedtransporterexpressionanddifferentiation.JCellSci,117,4077.

5.   BeuersU,DenkGU,SorokaCJ,WimmerR,RustC,PaumgartnerG,BoyerJL.(2003)Taurolithocholicacidexertscholestaticeffectsviaphosphatidylinositol3-kinase-dependentmechanismsinperfusedratliversandrathepatocytecouplets.JBiolChem,278,17810.

6.   KidaM,ManoY,UenoY,KobayashiK,GotoJ,IshiiM,ShimosegawaT.(2003)Vectorialtransportofbileacidsinimmortalizedmousebileductcells.HepatolRes,27,151.

7.   RomanID,Fernandez-MorenoMD,FueyoJA,RomaMG,ColemanR.(2003)CyclosporinAinducedinternalizationofthebilesaltexportpumpinisolatedrathepatocytecouplets.ToxicolSci,71,276.

8.   MilkiewiczP,RomaMG,EliasE,ColemanR.(2002)Hepatoprotectionwithtauroursodeoxycholateandbetamuricholateagainsttaurolithocholateinducedcholestasis:involvementofsignaltransductionpathways.Gut,51,113.

9.   CrocenziFA,SanchezPozziEJ,PellegrinoJM,FavreCO,RodriguezGarayEA,MottinoAD,ColemanR,RomaMG.(2001)Beneficialeffectsofsilymarinonestrogen-inducedcholestasisintherat:astudyinvivoandinisolatedhepatocytecouplets.Hepatology,34,329.

10.   HolzingerF,KrahenbuhlL,SchteingartCD,Ton-NuHT,HofmannAF.(2001)Useofafluorescentbileacidtoenhancevisualizationofthebiliarytractandbileleaksduringlaparoscopicsurgeryinrabbits.SurgEndosc,15,209.


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品牌介绍

AAT Bioquest常用产品报价单

产品名货号公司分类商城分类美金价
AAT Bioquest/Fluorescein, disodium salt *CAS 518-47-8*/2/100 mg2iFluor Rapid Tests酸碱缓冲液1088.00
AAT Bioquest/14-3-3 ζ (Ab-58) Antibody/8B0001/50 ug8B0001Signaling Intermediate Ab重组抗体2828.00
AAT Bioquest/Opioid Receptor (Phospho-Ser375) Antibody/8A0022/50 ug8A0022Phospho-Specific Ab受体2828.00
AAT Bioquest/iFluor™ 350 goat anti-mouse IgG (H+L)/16440/200 ug16440Fluorescent Anti-IgGs荧光染料1088.00
AAT Bioquest/trFluor™ Eu goat anti-mouse IgG (H+L)/16518/100 ug16518Fluorescent Anti-IgGs抗小鼠4278.00
AAT Bioquest/RPE-streptavidin conjugate/16900/100 ug16900Streptavidin Conjugates其他生物染料1378.00
AAT Bioquest/GCNT3 Antibody/8C14708/50 ug8C14708Signaling Intermediate Ab功能性抗体2828.00
AAT Bioquest/Amplite™ Luciferase Reporter Gene Assay Kit *Bright Glow*/12518/1 plate12518Reporter Gene Enzymes其它检测试剂盒2103.00
AAT Bioquest/ReadiLink™ Rapid mFluor™ Violet 450 Antibody Labeling Kit *Microscale Optimized for Labeling 50 &mi1100mFluor™ Dyes and Kits标记试剂盒2103.00
AAT Bioquest/Amplite™ Colorimetric Urea Quantitation Kit *Blue Color*/10058/200 Tests10058Diagnostic Molecules定量试剂盒2828.00
AAT Bioquest/Screen Quest™ CHO-Gqi Chimera Cell line/38101/Each38101cAMP GPCR Assays常规细胞株0.00
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