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主营:研究并生产荧光和发光探针,信号转导研究的试剂
℡ 4000-520-616
℡ 4000-520-616
AAT Bioquest/5-OG488 acid [equivalent to Oregon Green® 488 carboxylic acid, 5-isomer]/708/25 mg
产品编号:708
市  场 价:¥56560.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$2828.00
品      牌: AAT Bioquest
公      司:AAT Bioquest
公司分类:
AAT Bioquest/5-OG488 acid [equivalent to Oregon Green® 488 carboxylic acid, 5-isomer]/708/25 mg
商品介绍
Overview
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Ex/Em(nm)496/524
MW412.30
CAS#1027168-06-4
SolventDMSO
StorageF/D/L
CategoryPeptidesSynthesis
PeptideLabelingReagents
RelatedFluoresceins
Amine-ReactiveProbes
5-OG488acidisthesamemoleculetoOregonGreen®488carboxylicacid,5-isomer(OregonGreen®istheTrademarkofInvitrogen).ThisfluorinatedanalogoffluoresceinhashigherphotostABIlityandalowerpKa~4.7while5-FAMhaspKa~6.4.ThedecreasedpKaof5-OG488makesitsfluorescenceessentiallypHinsensitiveinthephysiologicalpHrange.Thisamine-reactive5-OG488canbeusedtomakebrightgreenfluorescentbioconjugateswithexcitation/emissionmaxima~496/524nm.Itisanexcellentreplacementto5-FITCthathasseverepHdependenceandlowphotostability.
SpectrumAdvancedSpectrumViewer

Sorry,yourbrowserdoesnotsupportinlineSVG.RelativeIntensity(%)100806040200Sorry,yourbrowserdoesnotsupportinlineSVG.
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References&Citations
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  1. LeeJS,FeijenJ.(2012)BiodegradablepolymersomesascarriersandreleasesystemsforpaclitaxelusingOregonGreen(R)488labeledpaclitaxelasamodelcompound.JControlRelease,158,312.
  2. LattaruloC,ThyssenD,KuchibholtaKV,HymanBT,BacskaiqBJ.(2011)Microscopicimagingofintracellularcalciuminlivecellsusinglifetime-basedratiometricmeasurementsofOregonGreenBAPTA-1.MethodsMolBiol,793,377.
  3. (2004)Cetuximab-OregonGreen488.In:MolecularImagingandContrastAgentDatabase(MICAD),Bethesda(MD).
  4. ChengKT,VanZandvoortM.(2004)Collagen-bindingadhesionprotein35-OregonGreen488.In:MolecularImagingandContrastAgentDatabase(MICAD),Bethesda(MD).
  5. LeeSJ,KimSJ,KimES,GeroskiDH,McCareyBE,EdelhauserHF.(2008)Trans-scleralpermeabilityofOregongreen488.JOculPharmacolTher,24,579.
  6. LeeSJ,KimES,GeroskiDH,McCareyBE,EdelhauserHF.(2008)PharmacokineticsofintraoculardrugdeliveryofOregongreen488-labeledtriamcinolonebysubtenoninjectionusingocularfluorophotometryinrabbiteyes.InvestOphthalmolVisSci,49,4506.
  7. ZeglisBM,BartonJK.(2006)Amismatch-selectivebifunctionalrhodium-OregonGreenconjugate:afluorescentprobeformismatchedDNA.JAmChemSoc,128,5654.
  8. MottramLF,BoonyarattanakalinS,KovelRE,PetersonBR.(2006)ThePennsylvaniaGreenFluorophore:ahybridofOregonGreenandTokyoGreenfortheconstructionofhydrophobicandpH-insensitiveMolecularprobes.OrgLett,8,581.
  9. RusinovaE,Tretyachenko-LadokhinaV,VeleOE,SenearDF,AlexanderRossJB.(2002)AlexaandOregonGreendyesasfluorescenceanisotropyprobesformeasuringprotein-proteinandprotein-nucleicacidinteractions.AnalBiochem,308,18.
  10. WhiteC,McGeownG.(2002)Imagingofchangesinsarcoplasmicreticulum[Ca(2+)]usingOregonGreenBAPTA5Nandconfocallaserscanningmicroscopy.CellCalcium,31,151.

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品牌介绍

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